Stemline Targeting cancer at its root
developing novel drugs that attack Cancer Stem Cells

Ownership Profile

Ownership Profile

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 137 397.06 79.66 24,674,760
Mutual Fund 150 127.93 24.77 7,673,937
Insider 10 61.24 11.52 3,567,238

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 77 61.70 12.42 3,848,571
Sellers 47 -39.90 8.07 -2,501,094
Net -- 21.80 4.35 1,347,477

Concentration

Value ($MM) % O/S Shares
Total Inst. 397.06 79.66 24,674,760
Top 10 Inst. 264.06 53.05 16,432,066
Top 20 Inst. 340.96 68.36 21,175,630
Top 50 Inst. 383.08 76.82 23,795,468

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Consonance Capital Management LP 2,747,198 8.87 140,600 6/30/18
Bergstein (Ivan) 2,481,431 8.01 325,000 9/12/18
Polar Capital LLP 1,912,605 6.17 1,539,320 6/30/18
BlackRock Institutional Trust Company, N.A. 1,665,711 5.38 214,098 6/30/18
Fidelity Management & Research Company 1,603,170 5.18 -389,871 7/31/18
Lyon Street Capital, LLC 1,471,518 4.75 230,225 6/30/18
The Vanguard Group, Inc. 1,259,542 4.07 148,043 6/30/18
Adage Capital Management, L.P. 1,160,014 3.74 -632,043 6/30/18
Eventide Asset Management, LLC 1,086,400 3.51 -- 6/30/18
State Street Global Advisors (US) 1,044,477 3.37 149,045 6/30/18
Citadel LLC 825,074 2.66 240,201 6/30/18
Hoberman (Kenneth) 684,594 2.21 275,000 9/12/18
Nexthera Capital LP 559,517 1.81 35,893 6/30/18
International Biotechnology Trust Plc 492,930 1.59 -- 6/30/18
AXA Investment Managers UK Ltd. 451,988 1.46 -112,516 6/30/18
Invus Public Equities Advisors, LLC 400,000 1.29 -- 6/30/18
Life Sciences Partners 377,592 1.22 -- 8/31/18
Northern Trust Investments, Inc. 345,186 1.11 40,888 6/30/18
Two Sigma Investments, LP 337,897 1.09 337,897 6/30/18
Geode Capital Management, L.L.C. 268,786 0.87 36,472 6/30/18
Point72 Asset Management, L.P. 215,000 0.69 -35,000 6/30/18
C WorldWide Asset Management Fondsmaeglerselskab A/S 213,706 0.69 43,711 6/30/18
D. E. Shaw & Co., L.P. 195,292 0.63 -55,129 6/30/18
Dimensional Fund Advisors, L.P. 177,731 0.57 -39,398 6/30/18
Millennium Management LLC 161,735 0.52 101,679 6/30/18
Medical Strategy GmbH 137,136 0.44 -- 7/31/18
Gionco (David G) 136,762 0.44 -43,213 4/23/18
Nuveen LLC 104,794 0.34 -27,282 6/30/18
J. Goldman & Co., L.P. 100,000 0.32 18,800 6/30/18
BlackRock Investment Management, LLC 93,802 0.30 1,064 6/30/18
BlackRock Financial Management, Inc. 90,651 0.29 63,898 6/30/18
Knott Partners Management, LLC 90,000 0.29 -- 6/30/18
Deutsche Asset Management Americas 82,643 0.27 41,045 6/30/18
BNY Mellon Asset Management 72,906 0.24 4,393 6/30/18
Forman (Alan S) 71,298 0.23 23,158 6/21/18
Morgan Stanley & Co. LLC 63,223 0.20 8,175 6/30/18
Charles Schwab Investment Management, Inc. 59,025 0.19 4,700 6/30/18
Neuberger Berman, LLC 52,500 0.17 52,500 6/30/18
Columbia Threadneedle Investments (US) 48,830 0.16 220 6/30/18
Virtus Etf Advisers LLC 45,850 0.15 -5,828 6/30/18
Credit Suisse Securities (USA) LLC 45,598 0.15 45,598 6/30/18
Zuerblis (Kenneth J) 45,121 0.15 23,158 6/21/18
Susquehanna International Group, LLP 44,765 0.14 44,765 6/30/18
Baker Bros. Advisors LP 44,524 0.14 -243,303 6/30/18
California State Teachers Retirement System 42,291 0.14 1,842 6/30/18
Bentsur (Ron) 40,443 0.13 23,158 6/21/18
Rhumbline Advisers Ltd. Partnership 38,788 0.13 12,732 6/30/18
Sard (Mark) 36,468 0.12 36,468 6/21/18
Northern Trust Global Investments 35,192 0.11 1,374 6/30/18
Empire Life Investments Inc. 33,764 0.11 151 6/30/18

* Insider values reflect direct beneficial ownership.



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