Stemline Targeting cancer at its root
developing novel drugs that attack Cancer Stem Cells

Ownership Profile

Ownership Profile

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 115 139.41 60.35 15,257,481
Mutual Fund 125 59.60 26.10 6,597,036
Insider 7 19.45 10.93 2,762,947

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 51 15.73 6.78 1,715,191
Sellers 61 -33.22 14.73 -3,724,868
Net -- -17.49 7.95 -2,009,677

Concentration

Value ($MM) % O/S Shares
Total Inst. 139.41 60.35 15,257,481
Top 10 Inst. 100.11 43.37 10,962,860
Top 20 Inst. 121.81 52.72 13,326,819
Top 50 Inst. 136.29 58.98 14,910,566

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company 2,538,892 10.04 -- 6/30/17
Bergstein (Ivan) 2,085,380 8.25 -- 4/20/17
BlackRock Institutional Trust Company, N.A. 1,213,712 4.80 96,186 6/30/17
Farallon Capital Management, L.L.C. 1,157,500 4.58 -10,000 6/30/17
Eventide Asset Management, LLC 1,086,400 4.30 -- 6/30/17
The Vanguard Group, Inc. 863,768 3.42 38,615 6/30/17
Baker Bros. Advisors LP 633,497 2.51 -- 6/30/17
AXA Investment Managers UK Ltd. 629,205 2.49 629,205 6/30/17
Hoberman (Kenneth) 409,143 1.62 1,269 4/20/17
State Street Global Advisors (US) 345,363 1.37 35,116 6/30/17
Millennium Management LLC 342,546 1.36 -85,677 6/30/17
Columbus Circle Investors 340,219 1.35 125,403 6/30/17
Sphera Funds Management Ltd. 300,000 1.19 -- 6/30/17
Northern Trust Investments, Inc. 261,384 1.03 41,672 6/30/17
Artal International S.C.A. 250,000 0.99 150,000 6/30/17
Sabby Management, LLC 187,500 0.74 -102,587 6/30/17
Medical Strategy GmbH 175,425 0.69 3,400 6/30/17
Oppenheim Asset Management Services S.à r.l. 173,299 0.69 57,550 6/30/17
Geode Capital Management, L.L.C. 167,373 0.66 7,453 6/30/17
Gionco (David G) 166,213 0.66 642 4/20/17
Lyon Street Capital, LLC 125,595 0.50 125,595 6/30/17
Dimensional Fund Advisors, L.P. 120,477 0.48 51,578 6/30/17
J. Goldman & Co., L.P. 120,000 0.47 -20,000 6/30/17
D. E. Shaw & Co., L.P. 102,284 0.40 88,782 6/30/17
Nuveen LLC 100,459 0.40 -4,596 6/30/17
Crestline Investors, Inc. 84,106 0.33 84,106 6/30/17
BlackRock Investment Management, LLC 83,964 0.33 3,864 6/30/17
Bailard, Inc. 83,785 0.33 -55,000 6/30/17
BNY Mellon Asset Management 65,079 0.26 -5,092 6/30/17
Pura Vida Investments, LLC 60,000 0.24 -- 6/30/17
Forman (Alan S) 58,140 0.23 10,000 6/19/17
Knott Partners Management, LLC 41,692 0.16 31,692 6/30/17
Apo Asset Management GmbH 41,389 0.16 -- 2/28/17
Charles Schwab Investment Management, Inc. 40,200 0.16 -- 6/30/17
California State Teachers Retirement System 40,049 0.16 -2,100 6/30/17
Columbia Threadneedle Investments (US) 37,880 0.15 -6,020 6/30/17
Trexquant Investment LP 33,017 0.13 -24,294 6/30/17
Zuerblis (Kenneth J) 31,963 0.13 10,000 6/19/17
Morgan Stanley & Co. LLC 31,228 0.12 290 6/30/17
California Public Employees' Retirement System 31,100 0.12 -- 6/30/17
Dobmeier (Eric L) 27,963 0.11 10,000 6/19/17
Rhumbline Advisers Ltd. Partnership 27,358 0.11 4,280 6/30/17
Bentsur (Ron) 27,285 0.11 10,000 6/19/17
PanAgora Asset Management Inc. 26,010 0.10 -72,273 6/30/17
Carl Domino, Inc. 26,000 0.10 -- 6/30/17
AQR Capital Management, LLC 25,562 0.10 -- 6/30/17
UBS Financial Services, Inc. 25,359 0.10 -1,586 6/30/17
Telemetry Investments, L.L.C. 25,000 0.10 1,470 6/30/17
Deutsche Asset Management Americas 20,465 0.08 20,206 6/30/17
A.R.T. Advisors, LLC 20,338 0.08 -14,700 6/30/17

* Insider values reflect direct beneficial ownership.



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