Stemline Targeting cancer at its root
developing novel drugs that attack Cancer Stem Cells

Ownership Profile

Ownership Profile

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 134 368.06 79.57 24,089,883
Mutual Fund 146 154.25 29.80 9,022,562
Insider 10 49.87 9.71 2,939,482

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 70 101.08 21.77 6,591,981
Sellers 51 -44.46 9.49 -2,871,639
Net -- 56.62 12.28 3,720,342

Concentration

Value ($MM) % O/S Shares
Total Inst. 368.06 79.57 24,089,883
Top 10 Inst. 245.97 53.10 16,076,355
Top 20 Inst. 311.00 67.01 20,285,716
Top 50 Inst. 356.01 76.90 23,279,210

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company 3,150,159 10.41 1,330,718 3/31/18
Consonance Capital Management LP 2,606,598 8.61 256,806 3/31/18
Bergstein (Ivan) 2,156,431 7.12 71,051 3/12/18
Adage Capital Management, L.P. 1,792,057 5.92 357,143 3/31/18
BlackRock Institutional Trust Company, N.A. 1,451,613 4.79 155,324 3/31/18
Lyon Street Capital, LLC 1,241,293 4.10 412,203 3/31/18
The Vanguard Group, Inc. 1,111,499 3.67 156,242 3/31/18
Eventide Asset Management, LLC 1,086,400 3.59 -- 3/31/18
State Street Global Advisors (US) 895,432 2.96 526,760 3/31/18
Citadel LLC 584,873 1.93 584,873 3/31/18
AXA Investment Managers UK Ltd. 564,504 1.86 14,275 3/31/18
venBio Select Advisor LLC 524,321 1.73 524,321 3/31/18
Nexthera Capital LP 523,624 1.73 523,624 3/31/18
International Biotechnology Trust Plc 492,930 1.63 -- 3/31/18
Hoberman (Kenneth) 407,532 1.35 10,372 3/13/18
Invus Public Equities Advisors, LLC 400,000 1.32 200,000 3/31/18
Polar Capital LLP 373,285 1.23 373,285 3/31/18
Life Sciences Partners 331,040 1.09 109,349 4/30/18
Northern Trust Investments, Inc. 304,298 1.01 40,443 3/31/18
Baker Bros. Advisors LP 287,827 0.95 -345,670 3/31/18
D. E. Shaw & Co., L.P. 250,421 0.83 57,588 3/31/18
Point72 Asset Management, L.P. 250,000 0.83 250,000 3/31/18
Geode Capital Management, L.L.C. 232,314 0.77 46,280 3/31/18
Dimensional Fund Advisors, L.P. 217,129 0.72 -- 3/31/18
Medical Strategy GmbH 206,553 0.68 44,117 4/30/18
Gionco (David G) 179,975 0.59 13,762 3/12/18
Hauck & Aufhäuser Asset Management Services S.à r.l. 173,299 0.57 -- 9/30/17
C WorldWide Asset Management Fondsmaeglerselskab A/S 169,995 0.56 -25,442 3/31/18
Nuveen LLC 132,076 0.44 38,237 3/31/18
BlackRock Investment Management, LLC 92,738 0.31 5,720 3/31/18
Knott Partners Management, LLC 90,000 0.30 15,008 3/31/18
J. Goldman & Co., L.P. 81,200 0.27 31,200 3/31/18
Invesco PowerShares Capital Management LLC 79,493 0.26 79,493 3/31/18
Lazard Asset Management, L.L.C. 78,034 0.26 78,034 3/31/18
BNY Mellon Asset Management 68,513 0.23 8,559 3/31/18
Millennium Management LLC 60,056 0.20 -229,949 3/31/18
Forman (Alan S) 58,140 0.19 10,000 6/19/17
Morgan Stanley & Co. LLC 55,048 0.18 10,065 3/31/18
Charles Schwab Investment Management, Inc. 54,325 0.18 7,300 3/31/18
UBS Financial Services, Inc. 51,877 0.17 40,304 3/31/18
Virtus Etf Advisers LLC 51,678 0.17 27,720 3/31/18
LifeSci Index Partners, LLC 51,678 0.17 -- 4/30/18
Columbia Threadneedle Investments (US) 48,610 0.16 -2,470 3/31/18
Deutsche Asset Management Americas 41,598 0.14 -8,747 3/31/18
BNY Mellon Asset Management North America Corporation 40,799 0.13 3,455 3/31/18
California State Teachers Retirement System 40,449 0.13 4,854 3/31/18
Crestline Investors, Inc. 38,102 0.13 -34,506 3/31/18
Northern Trust Global Investments 33,818 0.11 2,094 3/31/18
Empire Life Investments Inc. 33,613 0.11 -- 3/31/18
Zuerblis (Kenneth J) 31,963 0.11 10,000 6/19/17

* Insider values reflect direct beneficial ownership.



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