Stemline Targeting cancer at its root
developing novel drugs that attack Cancer Stem Cells

Ownership Profile

Ownership Profile

Shareholders

Shareholder Holders Value ($MM) % O/S Shares
Institution 121 136.81 56.14 14,100,723
Mutual Fund 128 65.50 28.99 7,280,743
Insider 3 18.63 10.59 2,660,736

Rotation

Shareholder Holders Value Chg ($MM) % O/S Share Change
Buyers 65 29.99 12.45 3,126,136
Sellers 30 -9.30 4.11 -1,032,278
Net -- 20.69 8.34 2,093,858

Concentration

Value ($MM) % O/S Shares
Total Inst. 136.81 56.14 14,100,723
Top 10 Inst. 95.43 39.54 9,929,470
Top 20 Inst. 116.97 48.10 12,079,649
Top 50 Inst. 133.79 54.77 13,756,802

Top Holders

Holder Shares Held % O/S Share Change Filing Date
Fidelity Management & Research Company 2,538,892 10.11 1,063,457 3/31/17
Bergstein (Ivan) 2,085,380 8.30 239,252 3/9/17
Franklin Advisers, Inc. 1,449,073 5.77 -193,124 12/31/16
Eventide Asset Management, LLC 851,400 3.39 -- 12/31/16
BlackRock Institutional Trust Company, N.A. 833,223 3.32 122,936 12/31/16
The Vanguard Group, Inc. 620,925 2.47 26,248 12/31/16
VHCP Management, LLC 451,400 1.80 -- 12/31/16
Hoberman (Kenneth) 407,874 1.62 110,482 3/9/17
Sabby Management, LLC 357,806 1.42 259,756 12/31/16
Baker Bros. Advisors LP 333,497 1.33 -- 12/31/16
Sphera Funds Management Ltd. 300,000 1.19 300,000 3/31/17
Farallon Capital Management, L.L.C. 257,500 1.03 257,500 12/31/16
State Street Global Advisors (US) 251,804 1.00 21,296 12/31/16
Medical Strategy GmbH 243,575 0.97 22,500 12/31/16
Columbus Circle Investors 214,816 0.86 117,187 3/31/17
J. Goldman & Co., L.P. 199,886 0.80 199,886 12/31/16
Northern Trust Investments, Inc. 189,629 0.76 14,885 12/31/16
Gionco (David G) 165,571 0.66 59,104 3/9/17
Millennium Management LLC 164,302 0.65 113,761 12/31/16
Invesco Canada Ltd. 163,096 0.65 41,202 12/31/16
Oppenheim Asset Management Services S.à r.l. 162,175 0.65 26,200 12/31/16
Geode Capital Management, L.L.C. 132,891 0.53 19,121 12/31/16
Bailard, Inc. 123,785 0.49 29,000 12/31/16
Bogle Investment Management, L.P. 94,945 0.38 94,945 12/31/16
TIAA Global Asset Management 89,506 0.36 -2,175 12/31/16
Dimensional Fund Advisors, L.P. 79,719 0.32 -2,100 12/31/16
BlackRock Investment Management, LLC 73,870 0.29 -23 12/31/16
BNY Mellon Asset Management 70,171 0.28 21,031 3/31/17
Susquehanna Financial Group, LLLP 68,922 0.27 68,922 12/31/16
Renaissance Technologies LLC 65,500 0.26 4,800 12/31/16
Compagnie Lombard, Odier SCA 60,500 0.24 -- 12/31/16
Trexquant Investment LP 57,311 0.23 57,311 3/31/17
PanAgora Asset Management Inc. 55,506 0.22 55,506 12/31/16
Morgan Stanley & Co. LLC 49,521 0.20 46,437 12/31/16
Forman (Alan S) 48,140 0.19 5,000 4/5/16
Columbia Threadneedle Investments (US) 43,900 0.17 3,500 3/31/17
Apo Asset Management GmbH 41,389 0.16 -- 2/28/17
California State Teachers Retirement System 34,749 0.14 -900 12/31/16
Oak Ridge Investments, LLC 34,153 0.14 21,357 12/31/16
D. E. Shaw & Co., L.P. 31,257 0.12 2,611 12/31/16
New York State Common Retirement Fund 31,200 0.12 -- 12/31/16
California Public Employees' Retirement System 31,100 0.12 -- 3/31/17
Carl Domino, Inc. 26,000 0.10 -- 3/31/17
Charles Schwab Investment Management, Inc. 26,000 0.10 -- 12/31/16
StoneRidge Investment Partners, LLC 25,323 0.10 -8,402 3/31/17
Telemetry Investments, L.L.C. 25,016 0.10 2,016 12/31/16
Jacobs Levy Equity Management, Inc. 24,954 0.10 -26,289 12/31/16
Buchi (J Kevin) 23,772 0.09 10,000 4/5/16
Rhumbline Advisers Ltd. Partnership 23,078 0.09 3,847 3/31/17
Paradigm Asset Management Company, L.L.C. 22,800 0.09 -700 12/31/16

* Insider values reflect direct beneficial ownership.



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